IMPACT OF PREGNANCY RELATED HORMONES ON DRUG METABOLIZING ENZYME AND TRANSPORT PROTEIN CONCENTRATIONS IN HUMAN HEPATOCYTES

Impact of pregnancy related hormones on drug metabolizing enzyme and transport protein concentrations in human hepatocytes

Pregnancy alters Memes the disposition and exposure to multiple drugs indicated for pregnancy-related complications.Previous in vitro studies have shown that pregnancy-related hormones (PRHs) alter the expression and function of certain cytochrome P450s (CYPs) in human hepatocytes.However, the impact of PRHs on hepatic concentrations of non-CYP dru

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DEBS – a unification theory for dry eye and blepharitis

James M Rynerson,1 Henry D Perry2 1BlephEx, LLC, Alvaton, KY, 2Department of Ophthalmology, Nassau University Medical Center, Hofstra University School of Medicine, East Meadow, NY, USA Abstract: For many years, blepharitis and dry eye disease have been thought to be two distinct diseases, and evaporative dry eye distinct from aqueous insufficiency

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Integration of Terrestrial and Drone-Borne Hyperspectral and Photogrammetric Sensing Methods for Exploration Mapping and Mining Monitoring

Mapping lithology and geological structures accurately remains a challenge in difficult terrain or in active mining areas.We demonstrate that the integration of terrestrial and drone-borne multi-sensor remote sensing techniques significantly improves the reliability, safety, and efficiency of geological activities during exploration and mining moni

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